No.b
| Database name
| Full name and/or description
| URL
|
|
| 1. Nucleotide Sequence Databases |
| 1.1. International Nucleotide Sequence Database Collaboration |
1 | DDBJ—DNA Data Bank of Japan | All known nucleotide and protein sequences | http://www.ddbj.nig.ac.jp/ |
2 | EMBL Nucleotide Sequence Database | All known nucleotide and protein sequences | http://www.ebi.ac.uk/embl.html |
3 | GenBank® | All known nucleotide and protein sequences | http://www.ncbi.nlm.nih.gov/Entrez |
| 1.2. DNA sequences: genes, motifs and regulatory sites |
| 1.2.1. Coding and coding DNA |
403 | ACLAME | A classification of genetic mobile elements | http://aclame.ulb.ac.be/ |
30 | CUTG | Codon usage tabulated from GenBank | http://www.kazusa.or.jp/codon/ |
480 | Genetic Codes | Genetic codes in various organisms and organelles | http://www.ncbi.nlm.nih.gov/Taxonomy/Utils/wprintgc.cgi |
668 | Entrez Gene | Gene-centered information at NCBI | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene |
495 | HERVd | Human endogenous retrovirus database | http://herv.img.cas.cz/ |
687 | Hoppsigen | Human and mouse homologous processed pseudogenes | http://pbil.univ-lyon1.fr/databases/hoppsigen.html |
294 | Imprinted Gene Catalogue | Imprinted genes and parent-of-origin effects in animals | http://www.otago.ac.nz/IGC |
512 | Islander | Pathogenicity islands and prophages in bacterial genomes | http://www.indiana.edu/~islander |
343 | MICdb | Prokaryotic microsatellites | http://www.cdfd.org.in/micas |
707 | NPRD | Nucleosome positioning region database | http://srs6.bionet.nsc.ru/srs6/ |
47 | STRBase | Short tandem DNA repeats database | http://www.cstl.nist.gov/div831/strbase/ |
5 | TIGR Gene Indices | Organism-specific databases of EST and gene sequences | http://www.tigr.org/tdb/tgi.shtml |
48 | Transterm | Codon usage, start and stop signals | http://uther.otago.ac.nz/Transterm.html |
6 | UniGene | Non-redundant set of eukaryotic gene-oriented clusters | http://www.ncbi.nlm.nih.gov/UniGene/ |
320 | UniVec | Vector sequences, adapters, linkers and primers used in DNA cloning, can be used to check for vector contamination | http://www.ncbi.nlm.nih.gov/VecScreen/UniVec.html |
302 | VectorDB | Characterization and classification of nucleic acid vectors | http://genome-www2.stanford.edu/vectordb/ |
305 | Xpro | Eukaryotic protein-encoding DNA sequences, both intron-containing and intron-less genes | http://origin.bic.nus.edu.sg/xpro/ |
| 1.2.2. Gene structure, introns and exons, splice sites |
414 | ASAP | Alternative spliced isoforms | http://www.bioinformatics.ucla.edu/ASAP |
28 | ASD | Alternative splicing database at EBI, includes three databases AltSplice, AltExtron and AEdb | http://www.ebi.ac.uk/asd |
10 | ASDB | Alternative splicing database: protein products and expression patterns of alternatively spliced genes | http://hazelton.lbl.gov/~teplitski/alt |
639 | ASHESdb | Alternatively spliced human genes by exon skipping database | http://sege.ntu.edu.sg/wester/ashes/ |
450 | EASED | Extended alternatively spliced EST database | http://eased.bioinf.mdc-berlin.de/ |
667 | ECgene | Genome annotation for alternative splicing | http://genome.ewha.ac.kr/ECgene/ |
631 | EDAS | EST-derived alternative splicing database | http://www.ig-msk.ru:8005/EDAS/ |
34 | ExInt | Exon–intron structure of eukaryotic genes | http://sege.ntu.edu.sg/wester/exint/ |
36 | HS3D | Homo sapiens splice sites dataset | http://www.sci.unisannio.it/docenti/rampone/ |
238 | Intronerator | Alternative splicing in C.elegans and C.briggsae | http://www.cse.ucsc.edu/~kent/intronerator/ |
46 | SpliceDB | Canonical and non-canonical mammalian splice sites | http://www.softberry.com/berry.phtml?topic=splicedb&group=data&subgroup=spldb |
746 | SpliceInfo | Modes of alternative splicing in human genome | http://140.115.50.96/SpliceInfo/ |
580 | SpliceNest | A tool for visualizing splicing of genes from EST data | http://splicenest.molgen.mpg.de/ |
| 1.2.3. Transcriptional regulator sites and transcription factors |
231 | ACTIVITY | Functional DNA/RNA site activity | http://wwwmgs.bionet.nsc.ru/mgs/systems/activity/ |
31 | DBTBS | Bacillus subtilis promoters and transcription factors | http://dbtbs.hgc.jp/ |
663 | DoOP | Database of orthologous promoters: chordates and plants | http://doop.abc.hu/ |
106 | DPInteract | Binding sites for E.coli DNA-binding proteins | http://arep.med.harvard.edu/dpinteract |
33 | EPD | Eukaryotic promoter database | http://www.epd.isb-sib.ch/ |
494 | HemoPDB | Hematopoietic promoter database: transcriptional regulation in hematopoiesis | http://bioinformatics.med.ohio-state.edu/HemoPDB |
516 | JASPAR | PSSMs for transcription factor DNA-binding sites | http://jaspar.cgb.ki.se/ |
700 | MAPPER | Putative transcription factor binding sites in various genomes | http://bio.chip.org/mapper |
40 | PLACE | Plant cis-acting regulatory DNA elements | http://www.dna.affrc.go.jp/htdocs/PLACE |
41 | PlantCARE | Plant promoters and cis-acting regulatory elements | http://intra.psb.ugent.be:8080/PlantCARE/ |
563 | PlantProm | Plant promoter sequences for RNA polymerase II | http://mendel.cs.rhul.ac.uk/ |
566 | PRODORIC | Prokaryotic database of gene regulation networks | http://prodoric.tu-bs.de/ |
42 | PromEC | E.coli promoters with experimentally identified transcriptional start sites | http://bioinfo.md.huji.ac.il/marg/promec |
246 | SELEX_DB | DNA and RNA binding sites for various proteins, found by systematic evolution of ligands by exponential enrichment | http://wwwmgs.bionet.nsc.ru/mgs/systems/selex/ |
227 | TESS | Transcription element search system | http://www.cbil.upenn.edu/tess |
756 | TRACTOR db | Transcription factors in gamma-proteobacteria database | http://www.tractor.lncc.br/ |
345 | TRANSCompel | Composite regulatory elements affecting gene transcription in eukaryotes | http://www.gene-regulation.com/pub/databases.html#transcompel |
340 | TRANSFAC | Transcription factors and binding sites | http://transfac.gbf.de/TRANSFAC/index.html |
757 | TRED | Transcriptional regulatory element database | http://rulai.cshl.edu/tred |
49 | TRRD | Transcription regulatory regions of eukaryotic genes | http://www.bionet.nsc.ru/trrd/ |
| 2. RNA sequence databases |
229 | 16S and 23S rRNA Mutation Database | 16S and 23S ribosomal RNA mutations | http://www.fandm.edu/Departments/Biology/Databases/RNA.html |
230 | 5S rRNA Database | 5S rRNA sequences | http://biobases.ibch.poznan.pl/5SData/ |
411 | Aptamer database | Small RNA/DNA molecules binding nucleic acids, proteins | http://aptamer.icmb.utexas.edu/ |
232 | ARED | AU-rich element-containing mRNA database | http://rc.kfshrc.edu.sa/ared |
378 | Mobile group II introns | A database of group II introns, self-splicing catalytic RNAs | http://www.fp.ucalgary.ca/group2introns/ |
463 | European rRNA database | All complete or nearly complete rRNA sequences | http://www.psb.ugent.be/rRNA/ |
490 | GtRDB | Genomic tRNA database | http://rna.wustl.edu/GtRDB |
236 | Guide RNA Database | RNA editing in various kinetoplastid species | http://biosun.bio.tu-darmstadt.de/goringer/gRNA/gRNA.html |
76 | HIV Sequence Database | HIV RNA sequences | http://hiv-web.lanl.gov/ |
689 | HuSiDa | Human siRNA database | http://itb1.biologie.hu-berlin.de/~nebulus/sirna/ |
237 | HyPaLib | Hybrid pattern library: structural elements in classes of RNA | http://bibiserv.techfak.uni-bielefeld.de/HyPa/ |
379 | IRESdb | Internal ribosome entry site database | http://ifr31w3.toulouse.inserm.fr/IRESdatabase/ |
529 | microRNA Registry | Database of microRNAs (small non-coding RNAs) | http://www.sanger.ac.uk/Software/Rfam/mirna/ |
380 | NCIR | Non-canonical interactions in RNA structures | http://prion.bchs.uh.edu/bp_type/ |
381 | ncRNAs Database | Non-coding RNAs with regulatory functions | http://biobases.ibch.poznan.pl/ncRNA/ |
705 | NONCODE | A database of non-coding RNAs | http://www.bioinfo.org.cn/NONCODE/index.htm |
240 | PLANTncRNAs | Plant non-coding RNAs | http://www.prl.msu.edu/PLANTncRNAs |
564 | Plant snoRNA DB | snoRNA genes in plant species | http://bioinf.scri.sari.ac.uk/cgi-bin/plant_snorna/home |
723 | PolyA_DB | A database of mammalian mRNA polyadenylation | http://polya.umdnj.edu/polyadb/ |
242 | PseudoBase | Database of RNA pseudoknots | http://wwwbio.leidenuniv.nl/~Batenburg/PKB.html |
382 | Rfam | Non-coding RNA families | http://www.sanger.ac.uk/Software/Rfam/ |
244 | RISSC | Ribosomal internal spacer sequence collection | http://ulises.umh.es/RISSC |
630 | RNAdb | Mammalian non-coding RNA database | http://ncrna.bioinformatics.com.au/ |
245 | RNA Modification Database | Naturally modified nucleosides in RNA | http://medlib.med.utah.edu/RNAmods/ |
43 | RRNDB | rRNA operon numbers in various prokaryotes | http://rrndb.cme.msu.edu/ |
629 | siRNAdb | siRNA database and search engine | http://sirna.cgb.ki.se/ |
247 | Small RNA Database | Small RNAs from prokaryotes and eukaryotes | http://mbcr.bcm.tmc.edu/smallRNA |
248 | SRPDB | Signal recognition particle database | http://psyche.uthct.edu/dbs/SRPDB/SRPDB.html |
754 | SSU rRNA Modification Database | Modified nucleosides in small subunit rRNA | http://medstat.med.utah.edu/SSUmods/ |
383 | Subviral RNA Database | Viroids and viroid-like RNAs | http://subviral.med.uottawa.ca/ |
249 | tmRNA Website | tmRNA sequences and alignments | http://www.indiana.edu/~tmrna |
250 | tmRDB | tmRNA database | http://psyche.uthct.edu/dbs/tmRDB/tmRDB.html |
251 | tRNA sequences | tRNA viewer and sequence editor | http://www.uni-bayreuth.de/departments/biochemie/trna/ |
252 | UTRdb/UTRsite | 5'- and 3'-UTRs of eukaryotic mRNAs | http://bighost.area.ba.cnr.it/srs6/ |
| 3. Protein sequence databases |
| 3.1. General sequence databases |
163 | EXProt | Sequences of proteins with experimentally verified function | http://www.cmbi.kun.nl/EXProt/ |
542 | NCBI Protein database | All protein sequences: translated from GenBank and imported from other protein databases | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Protein |
714 | PA-GOSUB | Protein sequences from model organisms, GO assignment and subcellular localization | http://www.cs.ualberta.ca/~bioinfo/PA/ProteomeIndex.html |
194 | PIR-PSD | Protein information resource protein sequence database, has been merged into the UniProt knowledgebase | http://pir.georgetown.edu/ |
370 | PIR-NREF | PIR's non-redundant reference protein database | http://pir.georgetown.edu/pirwww/pirnref.shtml |
565 | PRF | Protein research foundation database of peptides: sequences, literature and unnatural amino acids | http://www.prf.or.jp/en |
197 | Swiss-Prot | Now UniProt/Swiss-Prot: expertly curated protein sequence database, section of the UniProt knowledgebase | http://www.expasy.org/sprot |
198 | TrEMBL | Now UniProt/TrEMBL: computer-annotated translations of EMBL nucleotide sequence entries: section of the UniProt knowledgebase | http://www.expasy.org/sprot |
775 | UniParc | UniProt archive: a repository of all protein sequences, consisting only of unique identifiers and sequence | http://www.uniprot.org/database/archive.shtml |
318 | UniProt | Universal protein knowledgebase: merged data from Swiss-Prot, TrEMBL and PIR protein sequence databases | http://www.uniprot.org/ |
776 | UniRef | UniProt non-redundant reference database: clustered sets of related sequences (including splice variants and isoforms) | http://www.uniprot.org/database/nref.shtml |
| 3.2. Protein properties |
221 | AAindex | Physicochemical properties of amino acids | |
729 | ProNIT | Thermodynamic data on protein–nucleic acid interactions | http://gibk26.bse.kyutech.ac.jp/jouhou/pronit/pronit.html |
280 | ProTherm | Thermodynamic data for wild-type and mutant proteins | http://gibk26.bse.kyutech.ac.jp/jouhou/protherm/protherm.html |
772 | TECRdb | Thermodynamics of enzyme-catalyzed reactions | http://xpdb.nist.gov/enzyme_thermodynamics/ |
| 3.3. Protein localization and targeting |
444 | DBSubLoc | Database of protein subcellular localization | http://www.bioinfo.tsinghua.edu.cn/dbsubloc.html |
375 | NESbase | Nuclear export signals database | http://www.cbs.dtu.dk/databases/NESbase |
376 | NLSdb | Nuclear localization signals | http://cubic.bioc.columbia.edu/db/NLSdb/ |
704 | NMPdb | Nuclear matrix associated proteins database | http://www.rostlab.org/db/NMPdb/ |
706 | NOPdb | Nucleolar proteome database | http://www.lamondlab.com/NOPdb/ |
734 | PSORTdb | Protein subcellular localization in bacteria | http://db.psort.org/ |
745 | SPD | Secreted protein database | http://spd.cbi.pku.edu.cn/ |
587 | THGS | Transmembrane helices in genome sequences | http://pranag.physics.iisc.ernet.in/thgs/ |
589 | TMPDB | Experimentally characterized transmembrane topologies | http://bioinfo.si.hirosaki-u.ac.jp/~TMPDB/ |
| 3.4. Protein sequence motifs and active sites |
374 | ASC | Active sequence collection: biologically active peptides | http://bioinformatica.isa.cnr.it/ASC/ |
203 | Blocks | Alignments of conserved regions in protein families | http://blocks.fhcrc.org/ |
440 | CSA | Catalytic site atlas: active sites and catalytic residues in enzymes of known 3D structure | http://www.ebi.ac.uk/thornton-srv/databases/CSA/ |
438 | COMe | Co-ordination of metals etc.: classification of bioinorganic proteins (metalloproteins and some other complex proteins) | http://www.ebi.ac.uk/come |
771 | CopS | Comprehensive peptide signature database | http://203.195.151.46/copsv2/index.html |
666 | eBLOCKS | Highly conserved protein sequence blocks | http://fold.stanford.edu/eblocks/acsearch.html |
206 | eMOTIF | Protein sequence motif determination and searches | http://motif.stanford.edu/emotif |
179 | Metalloprotein Site Database | Metal-binding sites in metalloproteins | http://metallo.scripps.edu/ |
209 | O-GlycBase | O- and C-linked glycosylation sites in proteins | http://www.cbs.dtu.dk/databases/OGLYCBASE/ |
717 | PDBSite | 3D structure of protein functional sites | http://srs6.bionet.nsc.ru/srs6/ |
187 | Phospho.ELM | S/T/Y protein phosphorylation sites (formerly PhosphoBase) | http://phospho.elm.eu.org/ |
193 | PROMISE | Prosthetic centers and metal ions in protein active sites | http://metallo.scripps.edu/PROMISE |
215 | PROSITE | Biologically significant protein patterns and profiles | http://www.expasy.org/prosite |
732 | ProTeus | Signature sequences at the protein N- and C-termini | http://www.proteus.cs.huji.ac.il/ |
| 3.5. Protein domain databases; protein classification |
622 | ADDA | A database of protein domain classification | http://ekhidna.biocenter.helsinki.fi:8080/examples/servlets/adda/ |
204 | CDD | Conserved domain database, includes protein domains from Pfam, SMART, COG and KOG databases | http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml |
205 | CluSTr | Clusters of Swiss-Prot+TrEMBL proteins | http://www.ebi.ac.uk/clustr |
671 | FunShift | Functional divergence between the subfamilies of a protein domain family | http://funshift.cgb.ki.se/ |
200 | Hits | A database of protein domains and motifs | http://hits.isb-sib.ch/ |
207 | InterPro | Integrated resource of protein families, domains and functional sites | http://www.ebi.ac.uk/interpro |
208 | iProClass | Integrated protein classification database | http://pir.georgetown.edu/iproclass/ |
561 | PIRSF | Family/superfamily classification of whole proteins | http://pir.georgetown.edu/pirsf/ |
212 | PRINTS | Hierarchical gene family fingerprints | http://www.bioinf.man.ac.uk/dbbrowser/PRINTS/ |
210 | Pfam | Protein families: multiple sequence alignments and profile hidden Markov models of protein domains | http://www.sanger.ac.uk/Software/Pfam/ |
727 | PRECISE | Predicted and consensus interaction sites in enzymes | http://precise.bu.edu/precisedb/ |
214 | ProDom | Protein domain families | http://www.toulouse.inra.fr/prodom.html |
216 | ProtoMap | Hierarchical classification of Swiss-Prot proteins | http://protomap.cornell.edu/ |
567 | ProtoNet | Hierarchical clustering of Swiss-Prot proteins | http://www.protonet.cs.huji.ac.il/ |
740 | S4 | Structure-based sequence alignments of SCOP superfamilies | http://compbio.mds.qmw.ac.uk/~james/S4.shtml |
217 | SBASE | Protein domain sequences and tools | http://www.icgeb.org/sbase |
218 | SMART | Simple modular architecture research tool: signalling, extracellular and chromatin-associated protein domains | http://smart.embl-heidelberg.de/ |
219 | SUPFAM | Grouping of sequence families into superfamilies | http://pauling.mbu.iisc.ernet.in/~supfam |
220 | SYSTERS | Systematic re-searching and clustering of proteins | http://systers.molgen.mpg.de/ |
199 | TIGRFAMs | TIGR protein families adapted for functional annotation | http://www.tigr.org/TIGRFAMs |
| 3.6. Databases of individual protein families |
156 | AARSDB | Aminoacyl-tRNA synthetase database | http://rose.man.poznan.pl/aars/index.html |
308 | ASPD | Artificial selected proteins/peptides database | http://wwwmgs.bionet.nsc.ru/mgs/gnw/aspd/ |
158 | BacTregulators | Transcriptional regulators of AraC and TetR families | http://www.bactregulators.org/ |
364 | CSDBase | Cold shock domain-containing proteins | http://www.chemie.uni-marburg.de/~csdbase/ |
653 | CuticleDB | Structural proteins of Arthropod cuticle | http://bioinformatics.biol.uoa.gr/cuticleDB |
658 | DCCP | Database of copper-chelating proteins | http://sdbi.sdut.edu.cn/DCCP/en/index.php |
160 | DExH/D Family Database | DEAD-box, DEAH-box and DExH-box proteins | http://www.helicase.net/dexhd/dbhome.htm |
161 | Endogenous GPCR List | G protein-coupled receptors; expression in cell lines | http://www.tumor-gene.org/GPCR/gpcr.html |
162 | ESTHER | Esterases and other alpha/beta hydrolase enzymes | http://www.ensam.inra.fr/esther |
464 | EyeSite | Families of proteins functioning in the eye | http://eyesite.cryst.bbk.ac.uk/ |
166 | GPCRDB | G protein-coupled receptors database | http://www.gpcr.org/7tm/ |
679 | gpDB | G-proteins and their interaction with GPCRs | http://bioinformatics.biol.uoa.gr/gpDB |
167 | Histone Database | Histone fold sequences and structures | http://research.nhgri.nih.gov/histones/ |
169 | Homeobox Page | Homeobox proteins, classification and evolution | http://www.biosci.ki.se/groups/tbu/homeo.html |
293 | Hox-Pro | Homeobox genes database | http://www.iephb.nw.ru/labs/lab38/spirov/hox_pro/hox-pro00.html |
170 | Homeodomain Resource | Homeodomain sequences, structures and related genetic and genomic information | http://research.nhgri.nih.gov/homeodomain/ |
366 | HORDE | Human olfactory receptor data exploratorium | http://bioinfo.weizmann.ac.il/HORDE/ |
174 | InBase | Inteins (protein splicing elements) database: properties, sequences, bibliography | http://www.neb.com/neb/inteins.html |
518 | KinG—Kinases in Genomes | S/T/Y-specific protein kinases encoded in complete genomes | http://hodgkin.mbu.iisc.ernet.in/~king |
519 | Knottins | Database of knottins—small proteins with an unusual ‘disulfide through disulfide’ knot | http://knottin.cbs.cnrs.fr/ |
176 | LGICdb | Ligand-gated ion channel subunit sequences database | http://www.pasteur.fr/recherche/banques/LGIC/LGIC.html |
368 | Lipase Engineering Database | Sequence, structure and function of lipases and esterases | http://www.led.uni-stuttgart.de/ |
524 | LOX-DB | Mammalian, invertebrate, plant and fungal lipoxygenases | http://www.dkfz-heidelberg.de/spec/lox-db/ |
177 | MEROPS | Database of proteolytic enzymes (peptidases) | http://merops.sanger.ac.uk/ |
369 | NPD | Nuclear protein database | http://npd.hgu.mrc.ac.uk/ |
546 | NucleaRDB | Nuclear receptor superfamily | http://www.receptors.org/NR/ |
182 | Nuclear Receptor Resource | Nuclear receptor superfamily | http://nrr.georgetown.edu/NRR/nrrhome.htm |
183 | NUREBASE | Nuclear hormone receptors database | http://www.ens-lyon.fr/LBMC/laudet/nurebase.html |
184 | Olfactory Receptor Database | Sequences for olfactory receptor-like molecules | http://senselab.med.yale.edu/senselab/ordb/ |
185 | ooTFD | Object-oriented transcription factors database | http://www.ifti.org/ootfd |
188 | PKR | Protein kinase resource: sequences, enzymology, genetics and molecular and structural properties | http://pkr.sdsc.edu/html/index.shtml |
759 | PLPMDB | Pyridoxal-5'-phosphate dependent enzymes mutations | http://www.studiofmp.com/plpmdb/ |
609 | ProLysED | A database of bacterial protease systems | http://genome.ukm.my/prolyses/ |
192 | Prolysis | Proteases and natural and synthetic protease inhibitors | http://delphi.phys.univ-tours.fr/Prolysis/ |
224 | REBASE | Restriction enzymes and associated methylases | http://rebase.neb.com/rebase/rebase.html |
195 | Ribonuclease P Database | RNase P sequences, alignments and structures | http://www.mbio.ncsu.edu/RNaseP/home.html |
573 | RPG | Ribosomal protein gene database | http://ribosome.miyazaki-med.ac.jp/ |
575 | RTKdb | Receptor tyrosine kinase sequences | http://pbil.univ-lyon1.fr/RTKdb/ |
309 | S/MARt dB | Nuclear scaffold/matrix attached regions | http://smartdb.bioinf.med.uni-goettingen.de/ |
741 | Scorpion | Database of scorpion toxins | http://research.i2r.a-star.edu.sg:8080/scorpion/ |
372 | SDAP | Structural database of allergenic proteins and food allergens | http://fermi.utmb.edu/SDAP |
196 | SENTRA | Sensory signal transduction proteins | http://www-wit.mcs.anl.gov/sentra/ |
373 | SEVENS | 7-transmembrane helix receptors (G-protein-coupled) | http://sevens.cbrc.jp/ |
248 | SRPDB | Proteins of the signal recognition particles | http://bio.lundberg.gu.se/dbs/SRPDB/SRPDB.html |
314 | TrSDB | Transcription factor database | http://ibb.uab.es/trsdb |
399 | VKCDB | Voltage-gated potassium channel database | http://vkcdb.biology.ualberta.ca/ |
202 | Wnt Database | Wnt proteins and phenotypes | http://www.stanford.edu/~rnusse/wntwindow.html |
| 4. Structure Databases |
| 4.1. Small molecules |
646 | ChEBI | Chemical entities of biological interest | http://www.ebi.ac.uk/chebi/ |
261 | CSD | Cambridge structural database: crystal structure information for organic and metal-organic compounds | http://www.ccdc.cam.ac.uk/prods/csd/csd.html |
265 | HIC-Up | Hetero-compound Information Centre—Uppsala | http://xray.bmc.uu.se/hicup |
402 | AANT | Amino acid–nucleotide interaction database | http://aant.icmb.utexas.edu/ |
111 | Klotho | Collection and categorization of biological compounds | http://www.biocheminfo.org/klotho |
113 | LIGAND | Chemical compounds and reactions in biological pathways | |
615 | PDB-Ligand | 3D structures of small molecules bound to proteins and nucleic acids | http://www.idrtech.com/PDB-Ligand/ |
735 | PubChem | Structures and biological activities of small organic molecules | http://pubchem.ncbi.nlm.nih.gov/ |
| 4.2. Carbohydrates |
429 | CCSD | Complex carbohydrate structure database (CarbBank) | http://bssv01.lancs.ac.uk/gig/pages/gag/carbbank.htm |
652 | CSS | Carbohydrate structure suite: carbohydrate 3D structures derived from the PDB | http://www.dkfz.de/spec/css/ |
486 | Glycan | Carbohydrate database, part of the KEGG system | |
292 | GlycoSuiteDB | N- and O-linked glycan structures and biological sources | http://www.glycosuite.com/ |
535 | Monosaccharide Browser | Space-filling Fischer projections of monosaccharides | http://www.jonmaber.demon.co.uk/monosaccharide |
300 | SWEET-DB | Annotated carbohydrate structure and substance information | http://www.dkfz-heidelberg.de/spec2/sweetdb/ |
| 4.3. Nucleic acid structure |
272 | NDB | Nucleic acid-containing structures | http://ndbserver.rutgers.edu/ |
273 | NTDB | Thermodynamic data for nucleic acids | http://ntdb.chem.cuhk.edu.hk/ |
387 | RNABase | RNA-containing structures from PDB and NDB | http://www.rnabase.org/ |
283 | SCOR | Structural classification of RNA: RNA motifs by structure, function and tertiary interactions | http://scor.lbl.gov/ |
| 4.4. Protein structure |
413 | ArchDB | Automated classification of protein loop structures | http://gurion.imim.es/archdb |
255 | ASTRAL | Sequences of domains of known structure, selected subsets and sequence–structure correspondences | http://astral.stanford.edu/ |
288 | BAliBASE | A database for comparison of multiple sequence alignments | http://www-igbmc.u-strasbg.fr/BioInfo/BAliBASE2/index.html |
257 | BioMagResBank | NMR spectroscopic data for proteins and nucleic acids | http://www.bmrb.wisc.edu/ |
384 | CADB | Conformational angles in proteins database | http://cluster.physics.iisc.ernet.in/cadb/ |
258 | CATH | Protein domain structures database | http://www.biochem.ucl.ac.uk/bsm/cath_new |
259 | CE | 3D protein structure alignments | http://cl.sdsc.edu/ce.html |
260 | CKAAPs DB | Structurally similar proteins with dissimilar sequences | http://ckaap.sdsc.edu/ |
442 | Dali | Protein fold classification using the Dali search engine | http://www.bioinfo.biocenter.helsinki.fi:8080/dali/ |
385 | Decoys ‘R’ Us | Computer-generated protein conformations | http://dd.stanford.edu/ |
447 | DisProt | Database of Protein Disorder: proteins that lack fixed 3D structure in their native states | http://divac.ist.temple.edu/disprot |
448 | DomIns | Domain insertions in known protein structures | http://stash.mrc-lmb.cam.ac.uk/DomIns |
264 | DSDBASE | Native and modeled disulfide bonds in proteins | http://www.ncbs.res.in/~faculty/mini/dsdbase/dsdbase.html |
386 | DSMM | Database of simulated molecular motions | http://projects.villa-bosch.de/dbase/dsmm/ |
452 | eF-site | Electrostatic surface of Functional site: electrostatic potentials and hydrophobic properties of the active sites | http://ef-site.protein.osaka-u.ac.jp/eF-site |
674 | GenDiS | Genomic distribution of protein structural superfamilies | http://caps.ncbs.res.in/gendis/home.html |
472 | Gene3D | Precalculated structural assignments for whole genomes | http://www.biochem.ucl.ac.uk/bsm/cath_new/Gene3D/ |
489 | GTD | Genomic threading database: structural annotations of complete proteomes | http://bioinf.cs.ucl.ac.uk/GTD |
322 | GTOP | Protein fold predictions from genome sequences | http://spock.genes.nig.ac.jp/~genome/ |
360 | Het-PDB Navi | Hetero-atoms in protein structures | http://daisy.nagahama-i-bio.ac.jp/golab/hetpdbnavi.html |
498 | HOMSTRAD | Homologous structure alignment database: curated structure-based alignments for protein families | http://www-cryst.bioc.cam.ac.uk/homstrad |
267 | IMB Jena Image Library | Visualization and analysis of 3D biopolymer structures | http://www.imb-jena.de/IMAGE.html |
502 | IMGT/3Dstructure-DB | Sequences and 3D structures of vertebrate immunoglobulins, T cell receptors and MHC proteins | http://imgt3d.igh.cnrs.fr/ |
268 | ISSD | Integrated sequence–structure database | http://www.protein.bio.msu.su/issd |
269 | LPFC | Library of protein family core structures | http://www-smi.stanford.edu/projects/helix/LPFC |
270 | MMDB | NCBI's database of 3D structures, part of NCBI Entrez | http://www.ncbi.nlm.nih.gov/Structure |
456 | E-MSD | EBI's macromolecular structure database | http://www.ebi.ac.uk/msd |
331 | ModBase | Annotated comparative protein structure models | http://alto.compbio.ucsf.edu/modbase-cgi/index.cgi |
262 | MolMovDB | Database of macromolecular movements: descriptions of protein and macromolecular motions, including movies | http://bioinfo.mbb.yale.edu/MolMovDB/ |
274 | PALI | Phylogeny and alignment of homologous protein structures | http://pauling.mbu.iisc.ernet.in/~pali |
275 | PASS2 | Structural motifs of protein superfamilies | http://ncbs.res.in/~faculty/mini/campass/pass.html |
557 | PepConfDB | A database of peptide conformations | http://www.peptidome.org/products/list.htm |
276 | PDB | Protein structure databank: all publicly available 3D structures of proteins and nucleic acids | http://www.rcsb.org/pdb |
277 | PDB-REPRDB | Representative protein chains, based on PDB entries | http://mbs.cbrc.jp/pdbreprdb-cgi/reprdb_menu.pl |
278 | PDBsum | Summaries and analyses of PDB structures | http://www.biochem.ucl.ac.uk/bsm/pdbsum |
619 | PDB_TM | Transmembrane proteins with known 3D structure | http://www.enzim.hu/PDB_TM/ |
719 | Protein Folding Database | Experimental data on protein folding | http://pfd.med.monash.edu.au/ |
282 | SCOP | Structural classification of proteins | http://scop.mrc-lmb.cam.ac.uk/scop |
284 | Sloop | Classification of protein loops | http://www-cryst.bioc.cam.ac.uk/~sloop/ |
583 | Structure Superposition Database | Pairwise superposition of TIM-barrel structures | http://ssd.rbvi.ucsf.edu/ |
585 | SWISS-MODEL Repository | Database of annotated 3D protein structure models | http://swissmodel.expasy.org/repository |
285 | SUPERFAMILY | Assignments of proteins to structural superfamilies | http://supfam.org/ |
584 | SURFACE | Surface residues and functions annotated, compared and evaluated: a database of protein surface patches | http://cbm.bio.uniroma2.it/surface |
764 | TargetDB | Target data from worldwide structural genomics projects | http://targetdb.pdb.org/ |
401 | 3D-GENOMICS | Structural annotations for complete proteomes | http://www.sbg.bio.ic.ac.uk/3dgenomics |
310 | TOPS | Topology of protein structures database | http://www.tops.leeds.ac.uk/ |
| 5. Genomics Databases (non-human) |
| 5.1. Genome annotation terms, ontologies and nomenclature |
73 | Genew | Human gene nomenclature: approved gene symbols | http://www.gene.ucl.ac.uk/nomenclature |
487 | GO | Gene ontology consortium database | http://www.geneontology.org/ |
389 | GOA | EBI's gene ontology annotation project | http://www.ebi.ac.uk/GOA |
513 | IUBMB Nomenclature database | Nomenclature of enzymes, membrane transporters, electron transport proteins and other proteins | http://www.chem.qmul.ac.uk/iubmb |
514 | IUPAC Nomenclature database | Nomenclature of biochemical and organic compounds approved by the IUBMB-IUPAC Joint Commission | http://www.chem.qmul.ac.uk/iupac |
515 | IUPHAR-RD | The International Union of Pharmacology recommendations on receptor nomenclature and drug classification | http://www.iuphar-db.org/iuphar-rd/ |
552 | PANTHER | Gene products organized by biological function | http://panther.celera.com/ |
317 | UMLS | Unified medical language system | http://umlsks.nlm.nih.gov/ |
| 5.1.1. Taxonomy and Identification |
78 | ICB | gyrB database for identification and classification of bacteria | http://seasquirt.mbio.co.jp/icb/index.php |
297 | NCBI Taxonomy | Names of all organisms represented in GenBank | http://www.ncbi.nlm.nih.gov/Taxonomy/ |
608 | PANDIT | Protein and associated nucleotide domains with inferred trees | http://www.ebi.ac.uk/goldman-srv/pandit/ |
299 | RIDOM | rRNA-based differentiation of medical microorganisms | http://www.ridom-rdna.de/ |
243 | RDP-II | Ribosomal database project | http://rdp.cme.msu.edu/ |
301 | Tree of Life | Information on phylogeny and biodiversity | http://phylogeny.arizona.edu/tree/phylogeny.html |
| 5.2. General genomics databases |
7 | COG | Clusters of orthologous groups of proteins | http://www.ncbi.nlm.nih.gov/COG |
650 | COGENT | Complete genome tracking: predicted peptides from fully sequenced genomes | http://maine.ebi.ac.uk:8000/services/cogent/ |
337 | CORG | Comparative regulatory genomics: conserved non-coding sequence blocks | http://corg.molgen.mpg.de/ |
445 | DEG | Database of essential genes from bacteria and yeast | http://tubic.tju.edu.cn/deg |
451 | EBI Genomes | EBI's collection of databases for the analysis of complete and unfinished viral, pro- and eukaryotic genomes | http://www.ebi.ac.uk/genomes |
453 | EGO | Eukaryotic gene orthologs: orthologous DNA sequences in the TIGR gene indices | http://www.tigr.org/tdb/tgi/ego/ |
70 | EMGlib | Enhanced microbial genomes library: completely sequenced genomes of unicellular organisms | http://pbil.univ-lyon1.fr/emglib/emglib.html |
458 | Entrez Genomes | NCBI's collection of databases for the analysis of complete and unfinished viral, pro- and eukaryotic genomes | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=Genome |
461 | ERGOLight | Integrated biochemical data on nine bacterial genomes: publicly available portion of the ERGO database | http://www.ergo-light.com/ERGO |
470 | FusionDB | Database of bacterial and archaeal gene fusion events | http://igs-server.cnrs-mrs.fr/FusionDB |
611 | Genome Atlas | DNA structural properties of sequenced genomes | http://www.cbs.dtu.dk/services/GenomeAtlas/ |
484 | Genome Information Broker | DDBJ's collection of databases for the analysis of complete and unfinished viral, pro- and eukaryotic genomes | http://gib.genes.nig.ac.jp/ |
678 | Genome Reviews | Integrated view of complete genomes | http://www.ebi.ac.uk/GenomeReviews/ |
75 | GOLD | Genomes online database: a listing of completed and ongoing genome projects | http://www.genomesonline.org/ |
352 | HGT-DB | Putative horizontally transferred genes in prokaryotic genomes | http://www.fut.es/~debb/HGT/ |
223 | Integr8 | Functional classification of proteins in whole genomes | http://www.ebi.ac.uk/integr8/ |
112 | KEGG | Kyoto encyclopedia of genes and genomes: integrated suite of databases on genes, proteins and metabolic pathways | http://www.genome.jp/kegg |
528 | MBGD | Microbial genome database for comparative analysis | |
549 | ORFanage | Database of orphan ORFs (ORFs with no homologs) in complete microbial genomes | http://www.cs.bgu.ac.il/~nomsiew/ORFans |
551 | PACRAT | Archaeal and bacterial intergenic sequence features | http://www.biosci.ohio-tate.edu/~pacrat |
715 | PartiGeneDB | Assembled partial genomes for 250 eukaryotic organisms | http://www.partigenedb.org/ |
354 | PEDANT | Results of an automated analysis of genomic sequences | http://pedant.gsf.de/ |
99 | TIGR Microbial Database | Lists of completed and ongoing genome projects with links to complete genome sequences | http://www.tigr.org/tdb/mdb/mdbcomplete.html |
66 | TIGR Comprehensive Microbial Resource | Various data on complete microbial genomes: uniform annotation, properties of DNA and predicted proteins | http://www.tigr.org/CMR |
311 | TransportDB | Predicted membrane transporters in complete genomes, classified according to the TC classification system | http://www.membranetransport.org/ |
118 | WIT3 | What is there? Metabolic reconstruction for completely sequenced microbial genomes | http://www-wit.mcs.anl.gov/wit3/ |
| 5.3. Organism-specific databases |
| 5.3.1. Viruses |
473 | HCVDB | The hepatitis C virus database | http://hepatitis.ibcp.fr/ |
497 | HIV Drug Resistance Database | HIV mutations that confer resistance to anti-HIV drugs | http://resdb.lanl.gov/Resist_DB/default.htm |
168 | HIV Molecular Immunology Database | HIV epitopes | http://hiv-web.lanl.gov/immunology/ |
365 | HIV RT and Protease Sequence Database | HIV reverse transcriptase and protease sequences | http://hivdb.stanford.edu/ |
602 | NCBI Viral Genomes | Viral genome resource at NCBI | http://www.ncbi.nlm.nih.gov/genomes/VIRUSES/viruses.html |
725 | Poxvirus.org | Poxvirus genomic sequences and gene annotation | http://www.poxvirus.org/ |
750 | T4-like genome database | Sequences of T4-like bacteriophages from various sources | http://phage.bioc.tulane.edu/ |
201 | VIDA | Homologous viral protein families database | http://www.biochem.ucl.ac.uk/bsm/virus_database/VIDA.html |
761 | VIPER | Virus particle explorer: virus capsid structures | http://mmtsb.scripps.edu/viper |
303 | VirOligo | Virus-specific oligonucleotides for PCR and hybridization | http://viroligo.okstate.edu/ |
| 5.3.2. Prokaryotes |
641 | BacMap | Picture atlas of annotated bacterial genomes | http://wishart.biology.ualberta.ca/BacMap |
614 | MetaGrowth | Growth requirements of bacterial pathogens | http://igs-server.cnrs-mrs.fr/axenic/ |
720 | PGTdb | Prokaryotic growth temperature database | http://pgtdb.csie.ncu.edu.tw/ |
| 5.3.2.1. Escherichia coli |
415 | ASAP | A systematic annotation package for community analysis of E.coli and related genomes | https://asap.ahabs.wisc.edu/annotation/php/ASAP1.htm |
428 | CyberCell database | A collection of data on E.coli K12 intended for mathematical modeling to simulate the bacterial cell | http://redpoll.pharmacy.ualberta.ca/CCDB |
436 | coliBase | A database for E.coli, Salmonella and Shigella | http://colibase.bham.ac.uk/ |
437 | Colibri | E.coli genome database at Institut Pasteur | http://genolist.pasteur.fr/Colibri/ |
623 | EchoBASE | Post-genomic studies of Escherichia coli | http://www.ecoli-york.org/ |
462 | Essential genes in E.coli | First results of an E.coli gene deletion project | http://www.genome.wisc.edu/resources/essential.htm |
482 | GenoBase | E.coli genome database at Nara Institute | http://ecoli.aist-nara.ac.jp/ |
165 | GenProtEC | E.coli K12 genome and proteome database | http://genprotec.mbl.edu/ |
555 | PEC | Profiling of E.coli chromosome | http://shigen.lab.nig.ac.jp/ecoli/pec |
108 | EcoCyc | E.coli K12 genes, metabolic pathways, transporters and gene regulation | http://ecocyc.org/ |
69 | EcoGene | Sequence and literature data on E.coli genes and proteins | http://bmb.med.miami.edu/EcoGene/EcoWeb/ |
116 | RegulonDB | Transcriptional regulation and operon organization in E.coli | http://www.cifn.unam.mx/Computational_Genomics/regulondb/ |
| 5.3.2.2. Bacillus subtilis |
424 | BSORF | Bacillus subtilis genome database at Kyoto U. | |
89 | NRSub | Non-redundant Bacillus subtilis database at U. Lyon | http://pbil.univ-lyon1.fr/nrsub/nrsub.html |
96 | SubtiList | Bacillus subtilis genome database at Institut Pasteur | http://genolist.pasteur.fr/SubtiList/ |
| 5.3.2.3. Other bacteria |
420 | BioCyc | Pathway/genome databases for many bacteria | http://biocyc.org/ |
426 | CampyDB | Database for Campylobacter genome analysis | http://campy.bham.ac.uk/ |
433 | ClostriDB | Finished and unfinished genomes of Clostridium spp. | http://clostri.bham.ac.uk/ |
648 | CIDB | Chlamydia Interactive Database: gene expression data | http://www.it.deakin.edu.au/CIDB |
68 | CyanoBase | Cyanobacterial genomes | http://www.kazusa.or.jp/cyano |
521 | LeptoList | Leptospira interrogans genome | http://bioinfo.hku.hk/LeptoList |
534 | MolliGen | Genomic data on mollicutes | http://cbi.labri.fr/outils/molligen/ |
733 | PseudoCAP | Pseudomonas aeruginosa genome database and community annotation project | http://www.pseudomonas.com/ |
94 | RsGDB | Rhodobacter sphaeroides genome | http://www.hgsc.bcm.tmc.edu/projects/microbial/Rsphaeroides/ |
762 | VirFact | Bacterial virulence factors and pathogenicity islands | http://virfact.burnham.org/ |
760 | Virulence Factors | Reference database for microbial virulence factors | http://zdsys.chgb.org.cn/VFs/main.htm |
| 5.3.3. Unicellular eukaryotes |
409 | ApiEST-DB | EST sequences from various Apicomplexan parasites | http://www.cbil.upenn.edu/paradbs-servlet |
439 | CryptoDB | Cryptosporidium parvum genome database | http://cryptodb.org/ |
662 | Diatom EST Database | ESTs from two diatom algae, Thalassiosira pseudonana and Phaeodactylum tricornutum | http://avesthagen.sznbowler.com/ |
446 | DictyBase | Universal resource for Dictyostelium discoideum | http://dictybase.org/ |
72 | Full-Malaria | Full-length cDNA library from erythrocytic-stage Plasmodium falciparum | http://fullmal.ims.u-tokyo.ac.jp/ |
328 | GeneDB | Curated database for various Sanger-sequenced genomes | http://www.genedb.org/ |
698 | LumbriBASE | ESTs of the earthworm Lumbricus rubellus | http://www.earthworms.org/ |
91 | PlasmoDB | Plasmodium genome database | http://plasmodb.org/ |
586 | TcruziDB | Trypanosoma cruzi genome database | http://tcruzidb.org/ |
359 | ToxoDB | Toxoplasma gondii genome database | http://toxodb.org/ |
| 5.3.4. Fungi |
| 5.3.4.1. Yeasts |
635 | AGD | Ashbya gossypii genome database | http://agd.unibas.ch/ |
617 | CandidaDB | Candida albicans genome database | http://genolist.pasteur.fr/CandidaDB |
645 | Candida Genome | Candida albicans genome database | http://www.candidagenome.org/ |
441 | CYGD | MIPS Comprehensive yeast genome database | http://mips.gsf.de/proj/yeast |
483 | Génolevures | A comparison of S.cerevisiae and 14 other yeast species | http://cbi.labri.fr/Genolevures |
730 | PROPHECY | Profiling of phenotypic characteristics in yeast | http://prophecy.lundberg.gu.se/ |
576 | SCMD | Saccharomyces cerevisiae morphological database: micrographs of budding yeast mutants | http://yeast.gi.k.u-tokyo.ac.jp/ |
577 | SCPD | Saccharomyces cerevisiae promoter database | http://cgsigma.cshl.org/jian |
357 | SGD | Saccharomyces genome database | http://www.yeastgenome.org/ |
25 | TRIPLES | Transposon-insertion phenotypes, localization and expression in Saccharomyces | http://ygac.med.yale.edu/triples/ |
306 | YDPM | Yeast deletion project and mitochondria database | http://www-deletion.stanford.edu/YDPM/YDPM_index.html |
342 | Yeast Intron Database | Ares lab database of splicesomal introns in S.cerevisiae | http://www.cse.ucsc.edu/research/compbio/yeast_introns.html |
254 | Yeast snoRNA Database | Yeast small nucleolar RNAs | http://www.bio.umass.edu/biochem/rna-sequence/Yeast_snoRNA_Database/snoRNA_DataBase.html |
307 | yMGV | Yeast microarray global viewer | http://www.transcriptome.ens.fr/ymgv/ |
763 | YRC PDR | Yeast resource center public data repository | http://www.yeastrc.org/pdr/ |
| 5.3.4.2. Other fungi |
425 | CADRE | Central Aspergillus data repository | http://www.cadre.man.ac.uk/ |
435 | COGEME | Phytopathogenic fungi and oomycete EST database | http://cogeme.ex.ac.uk/ |
533 | MNCDB | MIPS Neurospora crassa database | http://mips.gsf.de/proj/neurospora/ |
708 | OGD | Oomycete Genomics Database: ESTs and annotation | http://www.oomycete.net/ |
98 | Phytophthora Functional Genomics Database | ESTs and expression data from P.infestans and P.sojae | http://www.pfgd.org/pfgd/ |
| 5.3.5. Invertebrates |
| 5.3.5.1. Caenorhabditis elegans |
430 | C.elegans Project | Genome sequencing data at the Sanger Institute | http://www.sanger.ac.uk/Projects/C_elegans |
238 | Intronerator | Introns and splicing in C.elegans and C.briggsae | http://www.cse.ucsc.edu/~kent/intronerator/ |
570 | RNAiDB | RNAi phenotypic analysis of C.elegans genes | http://www.rnai.org/ |
100 | WILMA | C.elegans annotation database | http://www.came.sbg.ac.at/wilma/ |
304 | WorfDB | C.elegans ORFeome | http://worfdb.dfci.harvard.edu/ |
51 | WormBase | Data repository for C.elegans and C.briggsae: curated genome annotation, genetic and physical maps, pathways | http://www.wormbase.org/ |
| 5.3.5.2. Drosophila melanogaster |
71 | FlyBase | Drosophila sequences and genomic information | http://flybase.bio.indiana.edu/ |
767 | FlyBrain | Database of the Drosophila nervous system | http://flybrain.neurobio.arizona.edu/ |
670 | FlyMine | Integration of insect genomic and proteomic data | http://www.flymine.org/ |
467 | FlyTrap | Drosophila mutants created using GFP protein trap strategy | http://flytrap.med.yale.edu/ |
471 | GadFly | Genome annotation database of Drosophila | http://www.fruitfly.org/ |
677 | GeniSys | Enhancer- and promoter-inserted mutants of Drosophila | http://genisys.kaist.ac.kr:8080/ |
774 | DPDB | Drosophila polymorphism database | http://dpdb.uab.es/ |
449 | Drosophila microarray project | Data and tools for Drosophila gene expression studies | http://www.flyarrays.com/fruitfly |
509 | InterActive Fly | Drosophila genes and their roles in development | http://sdb.bio.purdue.edu/fly/aimain/1aahome.htm |
| 5.3.5.3. Other invertebrates |
410 | AppaDB | A database on the nematode Pristionchus pacificus | http://appadb.eb.tuebingen.mpg.de/ |
643 | BeetleBase | Genome database of the beetle Tribolium castaneum | http://www.bioinformatics.ksu.edu/BeetleBase/ |
649 | Ciliate IES-MDS Db | Macro- and micronuclear genes in spirotrichous ciliates | http://oxytricha.princeton.edu/dimorphism/database.htm |
434 | CnidBase | Cnidarian evolution and gene expression database | http://cnidbase.bu.edu/ |
543 | Nematode.net | Parasitic nematode sequencing project | http://nematode.net/ |
544 | NEMBASE | Nematode sequence and functional data database | http://www.nematodes.org/ |
726 | PPNEMA | Plant-parasitic nematode rRNAs | http://bighost.area.ba.cnr.it/PPNEMA/ |
743 | SilkDB | Silkworm Bombyx mori ESTs, mutants, photographs | http://www.ab.a.u-tokyo.ac.jp/genome/ |
744 | SilkSatDb | A microsatellite database of the silkworm Bombyx mori | http://www.cdfd.org.in/silksatdb/ |
747 | SpodoBase | Genomics of the butterfly Spodoptera frugiperda | http://bioweb.ensam.inra.fr/spodobase/ |
| 6. Metabolic Enzymes and Pathways; Signaling Pathways |
| 6.1. Enzymes and Enzyme Nomenclature |
421 | BRENDA | Enzyme names and biochemical properties | http://www.brenda.uni-koeln.de/ |
109 | ENZYME | Enzyme nomenclature and properties | http://www.expasy.org/enzyme |
459 | Enzyme Nomenclature | IUBMB Nomenclature Committee recommendations | http://www.chem.qmw.ac.uk/iubmb/enzyme |
613 | EzCatDB | Enzyme Catalytic Mechanism Database | http://mbs.cbrc.jp/EzCatDB/ |
508 | IntEnz | Integrated enzyme database and enzyme nomenclature | http://www.ebi.ac.uk/intenz |
716 | PDBrtf | Representation of target families of enzymes in PDB | http://cgl.imim.es/pdbrtf/ |
758 | SCOPEC | Mapping of catalytic function to domain structure | http://www.enzome.com/databases/scopec.php |
| 6.2. Metabolic Pathways |
644 | BioSilico | Integrated access to various metabolic databases | http://biosilico.kaist.ac.kr/ |
112 | KEGG Pathway | Metabolic and regulatory pathways in complete genomes | http://www.genome.jp/kegg/pathway.html |
114 | MetaCyc | Metabolic pathways and enzymes from various organisms | http://metacyc.org/ |
115 | PathDB | Biochemical pathways, compounds and metabolism | http://www.ncgr.org/pathdb |
117 | UM-BBD | University of Minnesota biocatalysis and biodegradation database | http://umbbd.ahc.umn.edu/ |
| 6.3. Intermolecular Interactions and Signaling Pathways |
633 | 3DID | 3D interacting domains: domain–domain interactions in proteins with known 3D structures | http://3did.embl.de/ |
405 | aMAZE | A system for the annotation, management, and analysis of biochemical and signalling pathway networks | http://www.amaze.ulb.ac.be/ |
103 | BIND | Biomolecular interaction network database | http://www.bind.ca/ |
419 | BioCarta | Online maps of metabolic and signaling pathways | http://www.biocarta.com/genes/allPathways.asp |
422 | BRITE | Biomolecular relations in information transmission and expression, part of KEGG | |
659 | DDIB | Database of domain interactions and binding | http://www.ddib.org/ |
104 | DIP | Database of interacting proteins: experimentally determined protein–protein interactions | http://dip.doe-mbi.ucla.edu/ |
105 | DRC | Database of ribosomal crosslinks | http://www.mpimg-berlin-dahlem.mpg.de/~ag_ribo/ag_brimacombe/drc |
329 | GeneNet | Database on gene network components | http://wwwmgs.bionet.nsc.ru/mgs/gnw/genenet |
664 | hp-DPI | Database of protein interactions in Helicobacter pylori | http://dpi.nhri.org.tw/hp/ |
688 | HPID | Human protein interaction database | http://www.hpid.org/ |
507 | IntAct project | Protein–protein interaction data | http://www.ebi.ac.uk/intact |
770 | Inter-Chain Beta-Sheets | Protein–protein interactions mediated by interchain beta-sheet formation | http://www.igb.uci.edu/servers/icbs/ |
510 | InterDom | Putative protein domain interactions | http://interdom.lit.org.sg/ |
718 | PDZBase | Protein–protein interactions involving PDZ domains | http://icb.med.cornell.edu/services/pdz/start |
749 | Protein-protein interfaces | Interacting residues in protein–protein interfaces in PDB | http://home.ku.edu.tr/~okeskin/INTERFACE/INTERFACES.html |
773 | PINdb | Proteins interacting in nucleus (human and yeast) | http://pin.mskcc.org/ |
748 | POINT | Prediction of human protein–protein interactome | http://point.nchc.org.tw/ |
616 | PSIbase | Interaction of proteins with known 3D structures | http://psimap.kaist.ac.kr/ |
612 | Reactome | A knowledgebase of biological pathways | http://www.reactome.org/ |
571 | ROSPath | Reactive oxygen species (ROS) signaling pathway | http://rospath.ewha.ac.kr/ |
395 | STCDB | Signal transductions classification database | http://bibiserv.techfak.uni-bielefeld.de/stcdb/ |
582 | STRING | Predicted functional associations between proteins | http://string.embl.de/ |
341 | TRANSPATH | Gene regulatory networks and microarray analysis | http://www.biobase.de/pages/products/databases.html |
| 7. Human and other Vertebrate Genomes |
| 7.1. Model organisms, comparative genomics |
63 | ACeDB | C.elegans, S.pombe and human genomic information | http://www.acedb.org/ |
26 | AllGenes | Human and mouse gene, transcript and protein annotation | http://www.allgenes.org/ |
65 | ArkDB | Genome databases for farm and other animals | http://www.thearkdb.org/ |
647 | ChickVD | Sequence variation in the chicken genome | http://chicken.genomics.org.cn/ |
286 | Cre Transgenic Database | Cre transgenic mouse lines with links to publications | http://www.mshri.on.ca/nagy/ |
660 | DED | Database of evolutionary distances | http://warta.bio.psu.edu/DED/ |
27 | Ensembl | Annotated information on eukaryotic genomes | http://www.ensembl.org/ |
465 | FANTOM | Functional annotation of mouse full-length cDNA clones | http://fantom2.gsc.riken.go.jp/ |
468 | FREP | Functional repeats in mouse cDNAs | http://facts.gsc.riken.go.jp/FREP/ |
673 | GALA | Genomic alignment, annotation and experimental results | http://gala.cse.psu.edu/ |
347 | GenetPig | Genes controlling economic traits in pig | http://www.infobiogen.fr/services/Genetpig |
605 | HomoloGene | Automatically detected homologous genes in complete eukaryotic genomes | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=homologene |
690 | Inparanoid | A database of eukaryotic orthologs | http://inparanoid.cgb.ki.se/ |
696 | IPI | International protein index: non-redundant sets of human, mouse and rat proteins | http://www.ebi.ac.uk/IPI |
777 | KaryotypeDB | Karyotype and chromosome information for animal and plant species | http://www.nenno.it/karyotypedb/ |
400 | KOG | Eukaryotic orthologous groups of proteins | http://www.ncbi.nlm.nih.gov/COG/new/shokog.cgi |
87 | Mouse Genome Informatics | Formerly mouse genome database | http://www.informatics.jax.org/ |
540 | MTID | Mouse transposon insertion database | http://mouse.ccgb.umn.edu/transposon/ |
703 | NegProt | Negative Proteome: a tool for comparison of complete proteomes | http://superfly.ucsd.edu/negprot |
556 | PEDE | Pig EST data explorer: full-length cDNAs and ESTs | http://pede.gene.staff.or.jp/ |
665 | PhenomicDB | Comparison of phenotypes of orthologous genes in human and model organisms | http://www.phenomicdb.de/ |
724 | Polymorphix | A database of sequence polymorphisms | http://pbil.univ-lyon1.fr/polymorphix/query.php |
93 | Rat Genome Database | Rat genetic and genomic data | http://rgd.mcw.edu/ |
625 | RatMap | Rat genome tools and data | http://ratmap.org/ |
751 | TAED | The adaptive evolution database: a phylogeny-based tool for comparative genomics | http://www.bioinfo.no/tools/TAED |
5 | TIGR Gene Indices | Organism-specific databases of EST and gene sequences | http://www.tigr.org/tdb/tgi.shtml |
6 | UniGene | Unified clusters of ESTs and full-length mRNA sequences | http://www.ncbi.nlm.nih.gov/UniGene/ |
319 | UniSTS | Unified view of sequence tagged sites with mapping data | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=unists |
783 | VEGA | Vertebrate genome annotation: a repository for manual annotation of finished vertebrate genome sequences | http://vega.sanger.ac.uk/ |
101 | ZFIN | Zebrafish information network | http://zfin.org/ |
| 7.2. Human genome databases, maps and viewers |
27 | Ensembl | Annotated information on eukaryotic genomes | http://www.ensembl.org/ |
404 | AluGene | Complete Alu map in the human genome | http://alugene.tau.ac.il/ |
349 | CroW 21 | Human chromosome 21 database | http://bioinfo.weizmann.ac.il/crow21/ |
55 | GB4-RH | Genebridge4 human radiation hybrid maps | http://www.sanger.ac.uk/Software/RHserver/RHserver.shtml |
56 | GDB | Human genes and genomic maps | http://www.gdb.org/ |
57 | GenAtlas | Human genes, markers and phenotypes | http://www.genatlas.org/ |
350 | GeneCards | Integrated database of human genes, maps, proteins and diseases | http://bioinfo.weizmann.ac.il/cards/ |
348 | GeneLoc | Gene location database (formerly UDB—Unified database for human genome mapping) | http://genecards.weizmann.ac.il/geneloc/ |
327 | GeneNest | Gene indices of human, mouse, zebrafish, etc. | http://genenest.molgen.mpg.de/ |
59 | GenMapDB | Mapped human BAC clones | http://genomics.med.upenn.edu/genmapdb |
35 | Gene Resource Locator | Alignment of ESTs with finished human sequence | http://grl.gi.k.u-tokyo.ac.jp/ |
324 | HOWDY | Human organized whole genome database | http://www-alis.tokyo.jst.go.jp/HOWDY/ |
60 | HuGeMap | Human genome genetic and physical map data | http://www.infobiogen.fr/services/Hugemap |
77 | Human BAC Ends | Non-redundant human BAC end sequences | http://www.tigr.org/tdb/humgen/bac_end_search/bac_end_intro.html |
597 | Human Genome Segmental Duplication Database | Segmental duplications in the human genome | http://projects.tcag.ca/humandup |
61 | IXDB | Physical maps of human chromosome X | http://ixdb.mpimg-berlin-dahlem.mpg.de/ |
697 | L1Base | Functional annotation and prediction of LINE-1 elements | http://line1.molgen.mpg.de/ |
54 | Map Viewer | Display of genomic information by chromosomal position | http://www.ncbi.nlm.nih.gov/mapview/ |
600 | MGC | Mammalian genome collection: full-length ORFs for human, mouse and rat genes | http://mgc.nci.nih.gov/ |
391 | NCBI RefSeq | Non-redundant collection of naturally occurring biological molecules | http://www.ncbi.nlm.nih.gov/RefSeq/ |
553 | ParaDB | Paralogy mapping in human genomes | http://abi.marseille.inserm.fr/paradb/ |
62 | RHdb | Radiation hybrid map data | http://www.ebi.ac.uk/RHdb |
592 | SKY/M-FISH and CGH | Fluorescent images of chromosomes and cytogenetic data | http://www.ncbi.nlm.nih.gov/sky/ |
4 | STACK | Sequence tag alignment and consensus knowledgebase | http://www.sanbi.ac.za/Dbases.html |
596 | The Chromosome 7 Annotation Project | A comprehensive description of human chromosome 7 | http://www.chr7.org/ |
684 | TRBase | Tandem repeats in the human genome | http://bioinfo.ex.ac.uk/trbase |
316 | UCSC Genome Browser | Genome assemblies and annotation | http://genome.ucsc.edu/ |
| 7.3. Human proteins |
685 | H-InvDB | Full-length human cDNA clones | http://www.h-invitational.jp/ |
499 | HPMR | Human plasma membrane receptome: sequences, literature and expression data | http://receptome.stanford.edu/ |
500 | HPRD | Human protein reference database: domain architecture, post-translational modifications and disease association | http://www.hprd.org/ |
37 | HUNT | Human novel transcripts: annotated full-length cDNAs | http://www.hri.co.jp/HUNT |
171 | HUGE | Human unidentified gene-encoded large (>50 kDa) protein and cDNA sequences | http://www.kazusa.or.jp/huge |
522 | LIFEdb | Localization, interaction and functions of human proteins | http://www.dkfz.de/LIFEdb |
312 | trome, trEST and trGEN: | Databases of predicted human protein sequences | ftp://ftp.isrec.isb-sib.ch/pub/databases/ |
| 8. Human Genes and Diseases |
| 8.1. General Databases |
661 | DG-CST | Disease gene conserved sequence tags | http://143.225.208.11/cst3/ |
683 | HCAD | Human chromosome aberration database: chromosomal breakpoints and affected genes | http://www.pdg.cnb.uam.es/UniPub/HCAD/ |
8 | Homophila | Drosophila homologs of human disease genes to | http://superfly.ucsd.edu/homophila/ |
548 | OMIA | Online Mendelian inheritance in animals: a catalog of animal genetic and genomic disorders | http://www.angis.org.au/omia |
143 | OMIM | Online Mendelian inheritance in man: a catalog of human genetic and genomic disorders | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=OMIM |
550 | ORFDB | Collection of ORFs that are sold by Invitrogen | http://orf.invitrogen.com/ |
554 | PathBase | European mutant mice histopathology database: images | http://www.pathbase.net/ |
146 | PMD | Compilation of protein mutant data | http://pmd.ddbj.nig.ac.jp/ |
358 | SOURCE | Functional genomics resource for human, mouse and rat | http://source.stanford.edu/ |
| 8.2. Human Mutations Databases |
| 8.2.1. General polymorphism databases |
119 | ALFRED | Allele frequencies and DNA polymorphisms | http://alfred.med.yale.edu/ |
416 | BayGenomics | Genes relevant to cardiovascular and pulmonary disease | http://baygenomics.ucsf.edu/ |
654 | Cypriot national mutation database | Disease mutations in the Cypriot population | http://www.goldenhelix.org/cypriot/ |
655 | Database of Genomic Variants | Human genomic variants: frequency, segmental duplications and genome assembly gaps | http://projects.tcag.ca/variation/ |
595 | dbQSNP | Quantification of SNP allele frequencies database | http://qsnp.gen.kyushu-u.ac.jp/ |
127 | dbSNP | Database of single nucleotide polymorphisms | http://www.ncbi.nlm.nih.gov/SNP/ |
669 | FESD | Functional element SNPs database: SNPs located within promoters, UTRs, etc., of human genes | http://combio.kribb.re.kr/ksnp/resd/ |
496 | HGVS Databases | A compilation of human mutation databases | http://www.hgvs.org/ |
131 | HGVbase | Human genome variation database: curated human polymorphisms | http://hgvbase.cgb.ki.se/ |
133 | HGMD | Human gene mutation database | http://www.hgmd.org/ |
367 | IPD | Immuno polymorphism database | http://www.ebi.ac.uk/ipd |
517 | JSNP | Japanese SNP database | http://snp.ims.u-tokyo.ac.jp/ |
45 | rSNP Guide | SNPs in regulatory gene regions | http://wwwmgs.bionet.nsc.ru/mgs/systems/rsnp/ |
344 | SNP Consortium database | SNP Consortium data | http://snp.cshl.org/ |
626 | SNPeffect | Phenotypic effects of human coding SNPs | http://snpeffect.vib.be/ |
590 | TopoSNP | Topographic database of non-synonymous SNPs | http://gila.bioengr.uic.edu/snp/toposnp |
755 | TPMD | Taiwan polymorphic microsatellite marker database | http://tpmd.nhri.org.tw/ |
| 8.2.2. Cancer |
122 | Atlas of Genetics and Cytogenetics in Oncology and Haematology | Cancer-related genes, chromosomal abnormalities in oncology and haematology, and cancer-prone diseases | http://www.infobiogen.fr/services/chromcancer/ |
593 | Cancer Chromosomes | Cytogenetic, clinical and reference information on cancer-related aberrations | http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=cancerchromosomes |
431 | CGED | Cancer gene expression database | http://love2.aist-nara.ac.jp/CGED |
651 | COSMIC | Catalogue of somatic mutations in cancer: sequence data, samples and publications | http://www.sanger.ac.uk/perl/CGP/cosmic |
126 | Germline p53 Mutations | Mutations in human tumor and cell line p53 gene | http://www.lf2.cuni.cz/win/projects/germline_mut_p53.htm |
362 | IARC TP53 Database | Human TP53 somatic and germline mutations | http://www.iarc.fr/p53/ |
152 | MTB | Mouse tumor biology database: tumor types, genes, classification, incidence, pathology | http://tumor.informatics.jax.org/ |
709 | OncoMine | Cancer microarray data by gene or cancer type | http://www.oncomine.org/ |
153 | Oral Cancer Gene Database | Cellular and molecular data for genes involved in oral cancer | http://www.tumor-gene.org/Oral/oral.html |
148 | RB1 Gene Mutation DB | Mutations in the human retinoblastoma (RB1) gene | http://www.d-lohmann.de/Rb/ |
574 | RTCGD | Mouse retroviral tagged cancer gene database | http://rtcgd.ncifcrf.gov/ |
579 | SNP500Cancer | Re-sequenced SNPs from 102 reference samples | http://snp500cancer.nci.nih.gov/ |
149 | SV40 Large T-Antigen Mutants | Mutations in SV40 large tumor antigen gene | http://supernova.bio.pitt.edu/pipaslab/ |
155 | Tumor Gene Family Databases | Cellular, molecular and biological data about genes involved in various cancers | http://www.tumor-gene.org/tgdf.html |
| 8.2.3. Gene-, system- or disease-specific |
768 | ALPSbase | Autoimmune lymphoproliferative syndrome database | http://research.nhgri.nih.gov/alps/ |
120 | Androgen Receptor Gene Mutations Database | Mutations in the androgen receptor gene | http://www.mcgill.ca/androgendb/ |
123 | BTKbase | Mutation registry for X-linked agammaglobulinemia | http://bioinf.uta.fi/BTKbase/ |
594 | CarpeDB | Comprehensive database on the genetics of epilepsy | http://www.carpedb.ua.edu/ |
124 | CASRDB | Calcium-sensing receptor database: CASR mutations causing hypercalcemia and/or hyperparathyroidism | http://www.casrdb.mcgill.ca/ |
125 | Cytokine Gene Polymorphism in Human Disease | Cytokine gene polymorphism literature database | http://bris.ac.uk/pathandmicro/services/GAI/cytokine4.htm |
137 | Collagen Mutation Database | Human type I and type III collagen gene mutations | http://www.le.ac.uk/genetics/collagen/ |
460 | ERGDB | Estrogen responsive genes database | http://research.i2r.a-star.edu.sg/promoter/Ergdb-v11/ |
164 | FUNPEP | Low-complexity peptides capable of forming amyloid plaque | http://www.cmbi.kun.nl/swift/FUNPEP/gergo/ |
363 | GOLD.db | Genomics of lipid-associated disorders database | http://gold.tugraz.at/ |
129 | GRAP | Mutants of G-protein coupled receptors of family A | http://tinygrap.uit.no/GRAP/ |
130 | HaemB | Factor IX gene mutations, insertions and deletions | http://www.kcl.ac.uk/ip/petergreen/haemBdatabase.html |
491 | HbVar | Human hemoglobin variants and thalassemias | http://globin.cse.psu.edu/globin/hbvar |
680 | HAGR | Human ageing genomic resources: genes related to ageing in humans and model organisms | http://genomics.senescence.info/ |
134 | Human p53/hprt, rodent lacI/lacZ databases | Mutations at the human p53 and hprt genes; rodent transgenic lacI and lacZ mutations | http://www.ibiblio.org/dnam/mainpage.html |
135 | Human PAX2 Allelic Variant Database | Mutations in human PAX2 gene | http://pax2.hgu.mrc.ac.uk/ |
136 | Human PAX6 Allelic Variant Database | Mutations in human PAX6 gene | http://pax6.hgu.mrc.ac.uk/ |
506 | INFEVERS | Hereditary inflammatory disorder and familial mediterranean fever mutation data | http://fmf.igh.cnrs.fr/infevers |
139 | KinMutBase | Disease-causing protein kinase mutations | http://www.uta.fi/imt/bioinfo/KinMutBase/ |
523 | Lowe Syndrome Mutation Database | Mutations causing Lowe oculocerebrorenal syndrome | http://research.nhgri.nih.gov/lowe/ |
142 | NCL Mutation Database | Polymorphisms in neuronal ceroid lipofuscinoses genes | http://www.ucl.ac.uk/ncl/ |
144 | PAHdb | Mutations at the phenylalanine hydroxylase locus | http://www.mcgill.ca/pahdb/ |
559 | PGDB | Prostate and prostatic diseases gene database | http://www.ucsf.edu/pgdb/ |
145 | PHEXdb | PHEX mutations causing X-linked hypophosphatemia | http://www.phexdb.mcgill.ca/ |
147 | PTCH1 Mutation Database | Mutations and SNPs found in PTCH1 gene | http://www.cybergene.se/PTCH/ptchbase.html |
| SCAdb | Spinocerebellar ataxia candidate gene database | http://ymbc.ym.edu.tw/cgi-bin/SCA/list.cgi?display=map |
632 | T1Dbase | A resource for type 1 diabetes research | http://t1dbase.org/ |
752 | The Autism Chromosome Rearrangement Database | Curated collection of genomic features related to autism | http://projects.tcag.ca/autism |
753 | The Lafora Database | Mutations and polymorphisms associated with Lafora progressive myoclonus epilepsy | http://projects.tcag.ca/lafora/ |
| 9. Microarray Data and other Gene Expression Databases |
634 | 5'SAGE | 5'-end serial analysis of gene expression | http://5sage.gi.k.u-tokyo.ac.jp/ |
338 | ArrayExpress | Public collection of microarray gene expression data | http://www.ebi.ac.uk/arrayexpress |
11 | Axeldb | Gene expression in Xenopus laevis | http://www.dkfz-heidelberg.de/abt0135/axeldb.htm |
12 | BodyMap | Human and mouse gene expression data | http://bodymap.ims.u-tokyo.ac.jp/ |
417 | BGED | Brain gene expression database | http://love2.aist-nara.ac.jp/BGED |
432 | CleanEx | Expression reference database, linking heterogeneous expression data to facilitate cross-dataset comparisons | http://www.cleanex.isb-sib.ch/ |
657 | dbERGEII | Database of experimental results on gene expression: genomic alignment, annotation and experimental data | http://dberge.cse.psu.edu/menu.html |
454 | EICO DB | Expression-based imprint candidate organiser: a database for discovery of novel imprinted genes | http://fantom2.gsc.riken.jp/EICODB/ |
455 | emap Atlas | Edinburgh mouse atlas: a digital atlas of mouse embryo development and spatially mapped gene expression | http://genex.hgu.mrc.ac.uk/ |
13 | EPConDB | Endocrine pancreas consortium database | http://www.cbil.upenn.edu/EPConDB |
110 | EpoDB | Genes expressed during human erythropoiesis | http://www.cbil.upenn.edu/EpoDB/ |
14 | FlyView | Drosophila development and genetics | http://pbio07.uni-muenster.de/ |
326 | GeneAnnot | Revised annotation of Affymetrix human gene probe sets | http://genecards.weizmann.ac.il/geneannot/ |
325 | GeneNote | Human genes expression profiles in healthy tissues | http://genecards.weizmann.ac.il/genenote/ |
330 | GenePaint | Gene expression patterns in the mouse | http://www.genepaint.org/Frameset.html |
676 | GeneTide | A transcriptome-focused member of the GeneCards suite | http://genecards.weizmann.ac.il/genetide/ |
481 | GeneTrap | Expression patterns in an embryonic stem library of gene trap insertions | http://www.cmhd.ca/sub/genetrap.asp |
603 | GEO | Gene expression omnibus: gene expression profiles | http://www.ncbi.nlm.nih.gov/geo/ |
485 | GermOnline | Gene expression in mitotic and meiotic cell cycle | http://www.germonline.org/ |
15 | GXD | Mouse gene expression database | http://www.informatics.jax.org/menus/expression_menu.shtml |
681 | H-ANGEL | Human anatomic gene expression library | http://www.jbirc.aist.go.jp/hinv/index.jsp |
493 | HemBase | Genes expressed in differentiating human erythroid cells | http://hembase.niddk.nih.gov/ |
23 | HugeIndex | Expression levels of human genes in normal tissues | http://hugeindex.org/ |
17 | Kidney Development Database | Kidney development and gene expression | http://golgi.ana.ed.ac.uk/kidhome.html |
778 | LOLA | List of lists annotated: a comparison of gene sets identified in different microarray experiments | http://www.lola.gwu.edu/ |
18 | MAGEST | Ascidian (Halocynthia roretzi) gene expression patterns | |
699 | MAMEP | Molecular anatomy of the mouse embryo project: gene expression data on mouse embryos | http://mamep.molgen.mpg.de/ |
339 | MEPD | Medaka (freshwater fish Oryzias latipes) gene expression pattern database | http://www.embl.de/mepd/ |
19 | MethDB | DNA methylation data, patterns and profiles | http://www.methdb.de/ |
537 | Mouse SAGE | SAGE libraries from various mouse tissues and cell lines | http://mouse.biomed.cas.cz/sage |
541 | NASCarrays | Nottingham Arabidopsis Stock Centre microarray database | http://affymetrix.arabidopsis.info/ |
545 | NetAffx | Public Affymetrix probesets and annotations | http://www.affymetrix.com/ |
711 | Osteo-Promoter Database | Genes in osteogenic proliferation and differentiation | http://www.opd.tau.ac.il/ |
154 | PEDB | Prostate expression database: ESTs from prostate tissue and cell type-specific cDNA libraries | http://www.pedb.org/ |
558 | PEPR | Public expression profiling resource: expression profiles in a variety of diseases and conditions | http://microarray.cnmcresearch.org/pgadatatable.asp |
21 | RECODE | Genes using programmed translational recoding in their expression | http://recode.genetics.utah.edu/ |
568 | RefExA | Reference database for human gene expression analysis | http://www.lsbm.org/db/index_e.html |
739 | rOGED | Rat ovarian gene expression database | http://web5.mccs.uky.edu/kolab/rogedendo.aspx |
712 | SAGEmap | NCBI's resource for SAGE data from various organisms | http://www.ncbi.nlm.nih.gov/SAGE |
742 | SIEGE | Smoking Induced Epithelial Gene Expression | http://pulm.bumc.bu.edu/siegeDB |
22 | Stanford Microarray Database | Raw and normalized data from microarray experiments | http://genome-www.stanford.edu/microarray |
24 | Tooth Development Database | Gene expression in dental tissue | http://bite-it.helsinki.fi/ |
| 10. Proteomics Resources |
606 | 2D-PAGE | Proteome database system for microbial research | http://www.mpiib-berlin.mpg.de/2D-PAGE |
731 | DynaProt 2D | Proteome database of Lactococcus lactis | http://www.wzw.tum.de/proteomik/lactis/ |
222 | GelBank | 2D gel electrophoresis patterns of proteins from complete microbial genomes | http://gelbank.anl.gov/ |
710 | Open Proteomics Database | Mass-spectrometry-based proteomics data for human, yeast, E.coli and Mycobacterium | http://bioinformatics.icmb.utexas.edu/OPD/ |
377 | PEP | Predictions for entire proteomes: summarized analyses of protein sequences | http://cubic.bioc.columbia.edu/pep/ |
281 | RESID | Pre-, co- and post-translational protein modifications | http://www-nbrf.georgetown.edu/pirwww/dbinfo/resid.html |
225 | SWISS-2DPAGE | Annotated 2D gel electrophoresis database | http://www.expasy.org/ch2d/ |
| 11. Other Molecular Biology Databases |
| 11.1. Drugs and drug design |
407 | ANTIMIC | Database of natural antimicrobial peptides | http://research.i2r.a-star.edu.sg/Templar/DB/ANTIMIC/ |
781 | AOBase | Antisense oligonucleotide selection and design | http://www.bio-inf.net/aobase/ |
408 | APD | Antimicrobial peptide database | http://aps.unmc.edu/AP/main.php |
423 | BSD | Biodegradative strain database: microorganisms that can degrade aromatic and other organic compounds | http://bsd.cme.msu.edu/ |
443 | DART | Drug adverse reaction target database | http://xin.cz3.nus.edu.sg/group/drt/dart.asp |
701 | MetaRouter | Compounds and pathways related to bioremediation | http://pdg.cnb.uam.es/MetaRouter/ |
186 | Peptaibol | Peptaibol (antibiotic peptide) sequences | http://www.cryst.bbk.ac.uk/peptaibol/welcome.html |
392 | PharmGKB | Pharmacogenomics knowledge base: effect of genetic variation on drug responses | http://www.pharmgkb.org/ |
315 | TTD | Therapeutic target database | http://xin.cz3.nus.edu.sg/group/cjttd/ttd.asp |
| 11.2. Probes |
505 | IMGT/PRIMER-DB | Immunogenetics oligonucleotide primer database | http://imgt3d.igh.cnrs.fr/PrimerDB/Query_PrDB.pl |
296 | MPDB | Synthetic oligonucleotides useful as primers or probes | http://www.biotech.ist.unige.it/interlab/mpdb.html |
728 | PrimerPCR | PCR primers for eukaryotic and prokaryotic genes | http://bioinfo.ebc.ee/PrimerStudio/ |
390 | probeBase | rRNA-targeted oligonucleotide probe sequences, DNA microarray layouts and associated information | http://www.microbial-ecology.net/probebase |
736 | QPPD | Quantitative PCR Primer Database for human and mouse | http://web.ncifcrf.gov/rtp/GEL/primerdb/default.asp |
356 | RTPrimerDB | Real-time PCR primer and probe sequences | http://medgen.ugent.be/rtprimerdb/ |
| 11.3. Unclassified databases |
298 | PubMed | Citations and abstracts of biomedical literature | http://pubmed.gov/ |
256 | BioImage | Database of multidimensional biological images | http://www.bioimage.org/ |
| 12. Organelle Databases |
74 | GOBASE | Organelle genome database | http://megasun.bch.umontreal.ca/gobase/ |
547 | OGRe | Organelle genome retrieval system | http://ogre.mcmaster.ca/ |
601 | Organelle genomes | NCBI's organelle genome resource | http://www.ncbi.nlm.nih.gov/genomes/ORGANELLES/organelles.html |
722 | PLprot | Arabidopsis thaliana chloroplast protein database | http://www.pb.ipw.biol.ethz.ch/proteomics |
713 | Organelle DB | Organelle proteins and subcellular structures | http://organelledb.lsi.umich.edu/ |
| 12.1. Mitochondrial Genes and Proteins |
637 | AMPDB | Arabidopsis mitochondrial protein database | http://www.mitoz.bcs.uwa.edu.au/AMPDB/ |
686 | HMPD | Human mitochondrial protein database | http://bioinfo.nist.gov:8080/examples/servlets/index.html |
38 | HvrBase | Primate mitochondrial DNA control region sequences | http://www.hvrbase.org/ |
64 | Mitochondriome | Metazoan mitochondrial genes | http://www.ba.itb.cnr.it/mitochondriome |
83 | MitoDat | Mitochondrial proteins (predominantly human) | http://www-lecb.ncifcrf.gov/mitoDat/ |
226 | MitoDrome | Nuclear-encoded mitochondrial proteins of Drosophila | http://www2.ba.itb.cnr.it/MitoDrome/ |
84 | MitoMap | Human mitochondrial genome | http://www.mitomap.org/ |
85 | MitoNuc | Nuclear genes coding for mitochondrial proteins | http://www2.ba.itb.cnr.it/MitoNuc/ |
86 | MITOP2 | Mitochondrial proteins, genes and diseases | http://ihg.gsf.de/mitop2/start.jsp |
531 | MitoPD | Yeast mitochondrial protein database | http://bmerc-www.bu.edu/mito |
532 | MitoProteome | Experimentally described human mitochondrial proteins | http://www.mitoproteome.org/ |
538 | MPIMP | Mitochondrial protein import machinery of plants | http://millar3.biochem.uwa.edu.au/~lister/index.html |
241 | PLMItRNA | Plant mitochondrial tRNA | http://bighost.area.ba.cnr.it/PLMItRNA/ |
| 13. Plant Databases |
| 13.1. General plant databases |
599 | BarleyBase | Expression profiling of plant genomes | http://www.barleybase.org/ |
624 | CR-EST | Crop ESTs: barley, pea, wheat and potato | http://pgrc.ipk-gatersleben.de/cr-est/ |
67 | CropNet | Genome mapping in crop plants | http://ukcrop.net/ |
128 | FLAGdb++ | Integrative database about plant genomes | http://genoplante-info.infobiogen.fr/FLAGdb/ |
351 | GénoPlante-Info | Plant genomic data from the Génoplante consortium | http://genoplante-info.infobiogen.fr/ |
488 | GrainGenes | Genes and phenotypes of wheat, barley, rye, triticale, oats | http://wheat.pw.usda.gov/ or http://www.graingenes.org/ |
607 | Gramene | A resource for comparative grass genomics | http://www.gramene.org/ |
81 | Mendel | Annotated plant ESTs and STSs | http://www.mendel.ac.uk/ |
581 | openSputnik | Plant EST clustering and functional annotation | http://sputnik.btk.fi/ |
560 | PhytoProt | Clusters of (predicted) plant proteins | http://genoplante-info.infobiogen.fr/phytoprot |
721 | PlantMarkers | A database of predicted molecular markers from plants | http://markers.btk.fi/ |
355 | PlantGDB | Plant genome database: actively transcribed plant genes | http://www.plantgdb.org/ |
189 | PLANT-PIs | Plant protease inhibitors | http://bighost.area.ba.cnr.it/PLANT-PIs |
371 | PlantsP/PlantsT | Plant proteins involved in phosphorylation and transport | http://plantsp.sdsc.edu/ |
588 | TIGR plant repeat database | Classification of repetitive sequences in plant genomes | http://www.tigr.org/tdb/e2k1/plant.repeats |
313 | TropGENE DB | Genes and genomes of sugarcane, banana, cocoa | http://tropgenedb.cirad.fr/ |
| 13.2. Arabidopsis thaliana |
636 | AGNS | Arabidopsis GeneNet supplementary: gene expression and phenotypes of mutants and transgens | http://emj-pc.ics.uci.edu/mgs/dbases/agns |
618 | AGRIS | Arabidopsis gene regulatory information server: promoters, transcription factors and their target genes | http://arabidopsis.med.ohio-state.edu/ |
780 | Arabidopsis MPSS | Arabidopsis gene expression detected by massively parallel signature sequencing | http://mpss.udel.edu/at/ |
638 | Arabidopsis Nucleolar Protein Database | Comparative analysis of human and Arabidopsis nucleolar proteomes | http://bioinf.scri.sari.ac.uk/cgi-bin/atnopdb/proteome_comparison |
640 | ASRP | Arabidopsis thaliana small RNA project | http://cgrb.orst.edu/smallRNA/db/ |
412 | ARAMEMNON | Arabidopsis thaliana membrane proteins and transporters | http://aramemnon.botanik.uni-koeln.de/ |
765 | AthaMap | Genome-wide map of putative transcription factor binding sites in Arabidopsis thaliana | http://www.athamap.de/ |
427 | CATMA | Complete Arabidopsis transcriptome microarray | http://www.catma.org/ |
656 | DATF | Database of Arabidopsis transcription factors | http://datf.cbi.pku.edu.cn/ |
672 | GabiPD | Central database of the German Plant Genome Project | http://gabi.rzpd.de/ |
675 | GeneFarm | Expert annotation of Arabidopsis gene and protein families | http://genoplante-info.infobiogen.fr/Genefarm/ |
527 | MAtDB | MIPS Arabidopsis thaliana database | http://mips.gsf.de/proj/thal/db |
738 | RARGE | RIKEN Arabidopsis genome encyclopedia: cDNAs, mutants and microarray data | http://rarge.gsc.riken.jp/ |
578 | SeedGenes | Genes essential for Arabidopsis development | http://www.seedgenes.org/ |
97 | TAIR | The Arabidopsis information resource | http://www.arabidopsis.org/ |
627 | WAtDB | Wageningen Arabidopsis thaliana database: mutants, transgenic lines and natural variants | http://www.watdb.nl/ |
| 13.3. Rice |
418 | BGI-RISe | Beijing genomics institute rice information system | http://rise.genomics.org.cn/ |
79 | INE | Integrated rice genome explorer | http://rgp.dna.affrc.go.jp/giot/INE.html |
353 | IRIS | International rice information system | http://www.iris.irri.org/ |
536 | MOsDB | MIPS Oryza sativa database | http://mips.gsf.de/proj/plant/jsf/rice/index.jsp |
90 | Oryzabase | Rice genetics and genomics | http://www.shigen.nig.ac.jp/rice/oryzabase/ |
628 | Oryza Tag Line database | T-DNA insertion mutants of rice | http://genoplante-info.infobiogen.fr/OryzaTagLine/ |
737 | RAD | Rice annotation database | http://golgi.gs.dna.affrc.go.jp/SY-1102/rad/index.html |
336 | RiceGAAS | Rice genome automated annotation system | http://ricegaas.dna.affrc.go.jp/ |
569 | Rice PIPELINE | Unification tool for rice databases | http://cdna01.dna.affrc.go.jp/PIPE |
572 | Rice proteome database | Rice proteome database | http://gene64.dna.affrc.go.jp/RPD/main_en.html |
| 13.4. Other plants |
610 | Brassica ASTRA | A database for Brassica genomic research | http://hornbill.cspp.latrobe.edu.au/cgi-binpub/index.pl |
526 | MaizeGDB | Maize genetics and genomics database | http://www.maizegdb.org/ |
80 | LIS (formerly MGI) | Legume information server (formerly Medicago genome initiative): ESTs, gene expression and proteomic data | http://www.comparative-legumes.org/ |
539 | MtDB | Medicago trunculata genome database | http://www.medicago.org/MtDB |
620 | PoMaMo | Potato Maps and More: Potato genome data | https://gabi.rzpd.de/PoMaMo.html |
766 | SGMD | Soybean genomics and microarray database | http://psi081.ba.ars.usda.gov/SGMD/default.htm |
| 14. Immunological Databases |
642 | BCIpep | A database of B-cell epitopes | http://bioinformatics.uams.edu/mirror/bcipep/ |
604 | dbMHC | Genetic and clinical database of the human MHC | http://www.ncbi.nlm.nih.gov/mhc/ |
150 | FIMM | Functional molecular immunology data | http://research.i2r.a-star.edu.sg/fimm |
682 | Haptendb | Curated database of hapten molecules | http://www.imtech.res.in/raghava/haptendb/ |
779 | HLA Ligand/Motif | A database and search tool for HLA sequences | http://hlaligand.ouhsc.edu/ |
501 | IL2Rgbase | X-linked severe combined immunodeficiency mutations | http://research.nhgri.nih.gov/scid/ |
172 | IMGT | International immunogenetics information system: immunoglobulins, T cell receptors, MHC and RPI | http://imgt.cines.fr/ |
503 | IMGT/Gene-DB | Vertebrate immunoglobulin and T cell receptor genes | http://imgt.cines.fr/cgi-bin/GENElect.jv |
173 | IMGT/HLA | Polymorphism of human MHC and related genes | http://www.ebi.ac.uk/imgt/hla/ |
504 | IMGT/LIGM-DB | Immunoglobulin, T cell receptor and MHC nucleotide sequences from human and other vertebrates | http://imgt.cines.fr/cgi-bin/IMGTlect.jv |
16 | Interferon Stimulated Gene Database | Genes induced by treatment with interferons | http://www.lerner.ccf.org/labs/williams/xchip-html.cgi |
692 | IPD-ESTDAB | Immunologically characterized melanoma cell lines | http://www.ebi.ac.uk/ipd/estdab/ |
693 | IPD-HPA | Immuno polymorphism of human platelet antigens | http://www.ebi.ac.uk/ipd/hpa/ |
694 | IPD-KIR | Immuno polymorphism of killer-cell Ig-like receptors | http://www.ebi.ac.uk/ipd/kir/ |
691 | IPD-MHC | Sequences of the major histocompatibility complex | http://www.ebi.ac.uk/ipd/mhc/ |
361 | JenPep | Quantitative binding data for immunological protein–peptide interactions | http://www.jenner.ac.uk/Jenpep |
702 | MHCBN | A database of MHC binding and non-binding peptides | http://www.imtech.res.in/raghava/mhcbn/ |
181 | MHCPEP | MHC-binding peptides | http://wehih.wehi.edu.au/mhcpep/ |
107 | MPID | MHC—peptide interaction database | http://surya.bic.nus.edu.sg/mpid |
621 | VBASE2 | Variable genes from the Ig loci of human and mouse | http://www.vbase2.org/ |